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Zinc gluconate an easy absorbable form of zinc is an active ingredient of ImmuMax
ImmuMax - Composition and Mode of Action - 6
ZINC

Zinc is present in ImmuMax capsules only. There is no zinc in ImmuMax syrup, because syrup containing zinc does not have stability data jet. We plan to add zinc to ImmuMax syrup formula as soon as stability data will be completed. ImmuMax provides easy absorbable zinc in a form of zinc gluconate. Each capsule contains 35 mg of zinc gluconate providing 5 mg Zn++, which makes 50 % RDA (recommended daily allowance).

Zinc is an essential trace element for humans and it is vital for many biological functions and plays a crucial role in more than 300 enzymes in the human body. The adult body contains about 3 grams of zinc. Zinc is found in all parts of the body: it is in organs, tissues, bones, fluids and cells. Muscles and bones contain most of the body’s zinc (90%). Particularly high concentrations of zinc are in the prostate gland and semen.

Zinc and Immune System

Zinc is known to play a central role in the immune system, and zinc-deficient persons experience increased susceptibility to a variety of pathogens. The immunologic mechanisms whereby zinc modulates increased susceptibility to infection have been studied for several decades. It is clear that zinc affects multiple aspects of the immune system, from the barrier of the skin to gene regulation within lymphocytes. Zinc is crucial for normal development and function of cells mediating nonspecific immunity such as neutrophils and natural killer cells. Zinc deficiency also affects development of acquired immunity by preventing both the outgrowth and certain functions of T lymphocytes such as activation, Th1 cytokine production, and B lymphocyte help. Likewise, B lymphocyte development and anti-body production, particularly immunoglobulin G, is compromised. The macrophage, a pivotal cell in many immunologic functions, is adversely affected by zinc deficiency, which can dysregulate intracellular killing, cytokine production, and phagocytosis. The effects of zinc on these key immunologic mediators is rooted in the myriad roles for zinc in basic cellular functions such as DNA replication, RNA transcription, cell division, and cell activation. Apoptosis is potentiated by zinc deficiency. Zinc also functions as an antioxidant and can stabilize membranes. This review explores these aspects of zinc biology of the immune system and attempts to provide a biological basis for the altered host resistance to infections observed during zinc deficiency and supplementation.

Low zinc level (deficiency) increases risk of respiratory infection and risk of complications if infection occurs. The disease course might be heavier. Elderly people and people overusing alcohol are particularly imperiled to zinc deficiency. Meydani et al. → (American Journal of Clinical Nutrition).
Zinc supplementation in small children particularly in developing countries reduces risk of pneumonia and diarrhea and if it would come to disease, the process would be easier and shorter and would have better prognosis. Sources acc. to WHO: ( → 1), ( → 2), ( → 3).

Chosen Beneficial Effects of Zinc

Zinc is an essential element necessary for the normal function of all organs and body systems. Dietary supplementation of zinc has positive impact on the whole body just to list the most important issues:

  • Zinc - vital for growth and cell division. It is especially important during pregnancy, for the growing fetus whose cells are rapidly dividing. Zinc also helps to avoid congenital abnormalities and pre-term delivery. Zinc is vital in activating growth - height, weight and bone development - in infants, children and teenagers.
  • Zinc is important for our senses and particularly sight, smell and taste. High concentrations of zinc are found in the retina. With age the retinal zinc declines which seems to play a role in the development of age-related macular degeneration (AMD), which leads to partial or complete loss of vision. Zinc may also protect from night blindness and prevent the development of cataracts. Zinc activates areas of the brain that receive and process information from taste and smell sensors. Levels of zinc in plasma and zinc’s effect on other nutrients, like copper and manganese, influence appetite and taste preference. Zinc is also used in the treatment of anorexia.
  • Zinc is vital for sexual system of men. It helps maintain sperm count and mobility and normal levels of serum testosterone. Zinc protects the prostate gland from infection (prostatitis) and ultimately from enlargement (prostatic hypertrophy). It also maintains both woman and man libido. Zinc plays a vital role in fertility.
  • Zinc – vital for skin, hair and nails. It accelerates the renewal of the skin cells. Zinc creams are used for babies to soothe diaper rash and to heal cuts and wounds. Zinc has also proven effective in treating acne, a problem that affects especially adolescents, and zinc has been reported to have a positive effect on psoriasis, eczema and neurodermitis. Zinc is also used as an anti-inflammatory agent and can help sooth the skin tissue, particularly in cases of poison ivy, sunburn, blisters and certain gum diseases. Zinc is important for healthy hair. Insufficient zinc levels may result in loss of hair, hair that looks thin and dull and that goes grey early. There are also a number of shampoos which contain zinc to help prevent dandruff.
  • Zinc is important for digestive system health. Zinc deficiency may lead to peptic ulcer disease and digestive infection (baby diarrhea)

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Please notice! The presented product is a dietary supplement and this presentation does not intend to attribute to it the property of preventing, treating or curing any human disease, or does not refer to such properties. Exact to the Directive 2002/46/EC of the European Parliament and of the Council on 10 June 2002.